NOVEL SYNTHESIS OF SOME HETEROCYCLES AND THEIR MOLLUSCICIDAL ACTIVITY AGAINST THE DESTRUCTIVE LAND SNAIL, THEBA PISANA

Novel synthesis of some heterocycles and their molluscicidal activity against the destructive land snail, Theba pisana

Abstract Background Terrestrial snails, specifically Theba pisana, represent significant agricultural pests in the Mediterranean region, particularly in Egypt.They are gastropods that cause cleansing foam substantial damage to a variety of vegetation, rendering them important agricultural pests that result in economic losses.In response, we have de

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Regulation of eDHFR-tagged proteins with trimethoprim PROTACs

Abstract Temporal control of protein levels in cells and living animals can be used to improve our understanding of protein function.In addition, control of engineered proteins could be used in therapeutic applications.PRoteolysis-TArgeting Chimeras (PROTACs) have emerged as a small-molecule-driven strategy to achieve rapid, post-translational regu

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